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Clarithromycin, itraconazole inhibitors of cytochrome P-450 CYP 3A isoenzymes CYP3A results in increased systemic exposure to amlodipine.cerebrovascular, cardiovascular, renal, mortality However, the diminished response observed with these other antihypertensive drug classes is largely eliminated when β-blockers are administered concomitantly with a diuretic goodrx amlodipine 5mg when ACE inhibitors or angiotensin II receptor antagonists are administered concomitantly with a calcium-channel blocker or thiazide diuretic.

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