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The most adapted dosing schedule appeared to be: first bolus of 10 mg/kg after induction of anaesthesia and prior to skin incision, continuous infusion of 10 mg/kg/h or injection into the CPB pump prime at a dose adapted on the CPB procedure, either according to patient weight with a 10 mg/kg dose, either according to CPB pump prime volume, While studied in very few patients, the limited data suggest that continuous infusion is preferable, since it would maintain therapeutic plasma concentration throughout surgery. Tranexamic acid (cyklokapron) box 500 mg 30 package quantity.

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However, controlled studies assessing the efficacy and safety of topical tranexamic acid TA for the treatment of melasma is tranexamic acid skin pigmentation. To assess in a double blind, randomized, prospective study, the efficacy of topical 5% tranexamic acid versus vehicle for treatment of melasma.The initial volume of distribution is about 9 to 12 liters.

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It is also used to prevent or reduce bleeding during certain medical procedures eg, cervical surgery and to treat certain bleeding problems eg, nosebleeds, bleeding inside the eye, heavy menstrual periods in patients whose blood does not clot well.Oral Surg Oral Med Oral Pathol Oral Radiol.



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MacGillivray RG, Tarabichi SB, Hawari MF, Raoof NT. Tranexamic convalescent to reduce blood cheap after bilateral recurrent knee arthroplasty: a benign, randomized double blind study. J Arthroplasty. 24 28. ...