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Fluconazole
Clinical data
Trade namesDiflucan, Celozole, others
AHFS/Drugs.comMonograph
MedlinePlusa690002
License dataUS   FDA: fluconazole
Pregnancy categoryAU: D US: C (Risk not ruled out) (low dose)
Routes of administrationby mouth, IV, topical
ATC codeD01AC15 ( WHO ) J02AC01 ( WHO )
Legal status
Legal statusAU: S3 (Pharmacist only) / S4, UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability>90% (oral)
Protein binding11–12%
Metabolismliver 11%
Elimination half-life30 hours (range 20-50 hours)
Excretionkidney 61-88%

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DIFLUCAN. Suppressive therapy: Pediatric dose, 3 mg/kg qd. Most frequent: nausea, vomiting, abdominal pain, diarrhea. Do not administer with astemizole or  ...: Antiretroviral Therapy and Medical Management of Pediatric ...

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Fluconazole 50 mg daily given up to diflucan fluconazole 150 mg days has been shown not to effect testosterone plasma concentrations in males or steroid concentration in females of child-bearing age. luconazole 200 mg to 400 mg daily has no clinically significant effect on endogenous steroid levels or on ACTH stimulated response in healthy male volunteers. Executive Summary - The Global Fund Fluconazole is an alternative in patients who are less critically ill and who have no recent azole exposure.

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8The dosage of fluconazole in breastmilk with these maternal dosages is not sufficient to treat oral thrush in the infant.

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