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Robiotics may represent a viable alternative treatment strategy to antibiotic administration given concerns about antimicrobial efficacy and resistance in acute diarrhea 3, 12 Probiotics are classically defined as live, viable microorganisms that produce evidence of a health benefit when administered 13 Variable sources in dogs have been observed for the strains from the following bacterial genera: Lactobacillus, Enterococcus, Bacillus, Streptococcus, Bifidobacterium, Pediococcus, and Weissella 14 16 Clinical studies evaluating the impact of probiotics suggest possible prophylactic effects on diarrhea resulting from intense exercise or shelter environments.

recent placebo-controlled study concluded that probiotics may reduce the duration of clinical signs in dogs administered a combination probiotic for treatment of acute diarrhea from multiple causes 18 In a similar study, improved fecal quality following administration of a probiotic fermented milk product was reported 19 However, probiotic effects are likely condition- and strain-specific 12 Metronidazole is a nitroimidazole treating bv with metronidazole gel empirically prescribed for the treatment of acute and chronic treating bv with metronidazole gel diarrheal diseases 20 24 The mechanism of action for both antibacterial and antiprotozoal effects remains incompletely understood, but it is believed to inhibit bacterial DNA and induce oxidative damage primarily in anaerobic bacteria 25 The drug s effect on both Giardia and Clostridium spp.In a study in healthy individuals, pretreatment with cimetidine reportedly increased the plasma half-life and decreased total plasma clearance of metronidazole following a single IV dose of the anti-infective, possibly by inhibiting hepatic metabolism of metronidazole.

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Cochrane Database Syst Rev. A meta-analysis of bacterial vaginosis metronidazole Papanicolaou smear bacterial vaginosis metronidazole wet mount for the diagnosis of vaginal trichomoniasis. Am J Med. Multicenter comparison of clotrimazole vaginal tablets, oral metronidazole, and vaginal suppositories containing sulfanilamide, aminacrine hydrochloride, and allantoin in the treatment of symptomatic trichomoniasis.Because of the medication s unique properties, it can alleviate many disorders that are difficult to treat in other ways.

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Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies.Infants and children: 0 mg/kg/day IV/PO in 4 divided doses. Max: 4 g/day.

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