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Essential tremor occurs during active movement and when the limb is held in a fixed posture or position against gravity; the tremor usually is absent at rest, although, when it is of large amplitude, tremor occasionally may be evident at rest, particularly in geriatric patients.Whereas the stepping stone hypothesis presumes a predominantly physiological component of drug progression, the gateway theory is a social theory.

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We describe three infants with taking propranolol for the first time capillary hemangiomas who received treatment from the age of 3-4 months up to the end of the first year of life. The study was approved by the Ethics Committee of the Ophthalmic Research Center at Shahid Beheshti University of Medical Sciences.This may result in severe hypotension andbradycardia.

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