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In a two-way crossover study in which 12 healthy subjects received a single 500 mg dose of azithromycin two 250 mg tablets with or without a high fat meal, food was shown to increase Cmax by 23% but had no effect on AUC. When azithromycin oral suspension was administered with food to 28 adult healthy male subjects, Cmax increased by 56% and AUC was unchanged.

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